Ewing sarcoma is a type of tumor that forms from a certain kind of cell in bone or soft tissue. Ewing sarcoma may be found in the bones of the legs, arms, feet, hands, chest, pelvis, spine, or skull. It also may be found in the soft tissue of the trunk, arms, legs, head and neck, abdominal cavity, or other areas. Ewing sarcoma is most common in adolescents and young adults.

Signs & Symptoms

These and other signs and symptoms may be caused by Ewing sarcoma or by other conditions. Check with your child’s doctor if your child has any of the following:

  • Pain and/or swelling, usually in the arms, legs, chest, back, or pelvis
  • A lump (which may feel soft and warm) in the arms, legs, chest, or pelvis
  • Fever for no known reason
  • A bone that breaks for no known reason


Your OHC doctor will help you determine the best care plan for you.

Localized Ewing Sarcoma: Standard treatments include:

Metastatic Ewing Sarcoma: Standard treatments include:

  • Chemotherapy
  • Surgery
  • Radiation therapy

Recurrent Ewing Sarcoma: There is no standard treatment for recurrent Ewing sarcoma but treatment options may include the following:

  • Combination chemotherapy
  • Radiation therapy to bone tumors, as palliative therapy to relieve symptoms and improve the quality of life
  • Radiation therapy that may be followed by surgery to remove tumors that have spread to the lungs
  • High-dose chemotherapy with stem cell rescue
  • Targeted therapy with a monoclonal antibody.